Symbol: Name: ID: |
RRAGA Ras-related GTP binding A GFS:6053 |
Gene name: | RRAGA |
Chromosome: | 9p21.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | RAGA, FIP-1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1915691 | Rat Genome Database ID: | RGD:619804 |
HGNC ID: | HGNC:16963 | RefSeq IDs: | NM_006570 |
Entrez Gene ID: | 10670 | Ensembl Gene ID: | ENSG00000155876 |
VEGA IDs: | OTTHUMG00000019621 | UniProt ID: | Q7L523 |
UCSC ID: | uc003znj.2 | OMIM ID: | 612194 |
Pubmed: | PMID7499430 PMID 8995684 | ||
CCDS IDs: | CCDSCCDS6488.1 |
Ras-related GTP-binding protein A is a protein that in humans is encoded by the RRAGA gene.
Function: Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
Products for RRAGA gene
Catalog | Product Name | Application | Company |
GFS:E06053 | Ras-related GTP binding A; ELISA kit | ELISA | n/a |
GFS:A06053 | Ras-related GTP binding A; Anti | ANTIBODIES | n/a |
GFS:P06053 | Ras-related GTP binding A; Protien | Protien | n/a |