| Symbol: Name: ID: |
RTCD1 RNA terminal phosphate cyclase domain 1 GFS:6877 |
| Gene name: | RTCD1 |
| Chromosome: | 1p13.3 |
| Previous Symbols: | |
| Previous Names: | RTC domain containing 1 |
| Aliases: | RPC |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1913618 | Rat Genome Database ID: | RGD:1303111 |
| HGNC ID: | HGNC:17981 | RefSeq IDs: | NM_001130841 |
| Entrez Gene ID: | 8634 | Ensembl Gene ID: | ENSG00000137996 |
| VEGA IDs: | OTTHUMG00000010920 | UniProt ID: | O00442 |
| UCSC ID: | uc001dtd.2 | OMIM ID: | 611286 |
| Pubmed: | PMID9184239 | ||
| CCDS IDs: | CCDSCCDS768.1 CCDS CCDS44178.1 | ||
RNA 3-prime-terminal phosphate cyclase (RPC; EC 6.5.1.4) catalyzes the ATP-dependent conversion of a 3-prime phosphate to a 2-prime,3-prime-cyclic phosphodiester at the end of RNA (Genschik et al., 1997 [PubMed 9184239]).[supplied by OMIM, Mar 2008].
Function: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
Products for RTCD1 gene
| Catalog | Product Name | Application | Company |
| GFS:E06877 | RNA terminal phosphate cyclase domain 1; ELISA kit | ELISA | n/a |
| GFS:A06877 | RNA terminal phosphate cyclase domain 1; Anti | ANTIBODIES | n/a |
| GFS:P06877 | RNA terminal phosphate cyclase domain 1; Protien | Protien | n/a |
