Symbol: Name: ID: |
RMRP RNA component of mitochondrial RNA processing endoribonuclease GFS:30 |
Gene name: | RMRP |
Chromosome: | 9p21-p12 |
Previous Symbols: | CHH |
Previous Names: | cartilage-hair hypoplasia |
Aliases: | RMRPR, RRP2, NME1 |
Name Aliases: | |
Locus Type: | RNA, RNase |
Mouse Genome Database ID: | MGI:97937 | Rat Genome Database ID: | RGD:3580 |
HGNC ID: | HGNC:10031 | RefSeq IDs: | NR_003051 |
Entrez Gene ID: | 6023 | Ensembl Gene ID: | ENSG00000199916 |
VEGA IDs: | UniProt ID: | ||
UCSC ID: | uc003zxh.1 | OMIM ID: | 157660 |
Pubmed: | PMID11207361 PMID 1623519 | ||
CCDS IDs: |
RNA component of mitochondrial RNA processing endoribonuclease the RNA component of mitochondrial RNA processing endoribonuclease, which cleaves mitochondrial RNA at a priming site of mitochondrial DNA replication. This RNA also interacts with the telomerase reverse transcriptase catalytic subunit to form a distinct ribonucleoprotein complex that has RNA-dependent RNA polymerase activity and produces double-stranded RNAs that can be processed into small interfering RNA. Mutations in this gene are associated with cartilage-hair hypoplasia.
The enzyme is a ribonucleoprotein whose RNA component is a nuclear gene product. The RNA component is the first RNA encoded by a single-copy gene in the nucleus and imported into mitochondria. The RMRP gene is untranslated, i.e., it encodes an RNA, not a protein.
Products for RMRP gene
Catalog | Product Name | Application | Company |
GFS:E00030 | RNA component of mitochondrial RNA processing endoribonuclease; ELISA kit | ELISA | n/a |
GFS:A00030 | RNA component of mitochondrial RNA processing endoribonuclease; Anti | ANTIBODIES | n/a |
GFS:P00030 | RNA component of mitochondrial RNA processing endoribonuclease; Protien | Protien | n/a |