Symbol: Name: ID: |
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 GFS:7098 |
Gene name: | RBFOX1 |
Chromosome: | 16p13.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | A2BP1, FOX-1, HRNBP1 |
Name Aliases: | ataxin 2-binding protein 1, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1926224 | Rat Genome Database ID: | RGD:1311210 |
HGNC ID: | HGNC:18222 | RefSeq IDs: | NM_001142333 |
Entrez Gene ID: | 54715 | Ensembl Gene ID: | ENSG00000078328 |
VEGA IDs: | OTTHUMG00000129551 | UniProt ID: | Q9NWB1 |
UCSC ID: | OMIM ID: | 605104 | |
Pubmed: | PMID10814712 PMID 16260614 | ||
CCDS IDs: | CCDSCCDS10531.1 CCDS CCDS10532.1 CCDS CCDS45405.1 |
Fox-1 homolog A also known as ataxin 2-binding protein 1 (A2BP1) or hexaribonucleotide-binding protein 1 (HRNBP1) or RNA binding protein, fox-1 homolog (RBFOX1), is a protein that in humans is encoded by the RBFOX1 gene.
Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined. (provided by RefSeq)
Function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.
Products for RBFOX1 gene
Catalog | Product Name | Application | Company |
GFS:E07098 | RNA binding protein, fox-1 homolog (C. elegans) 1; ELISA kit | ELISA | n/a |
GFS:A07098 | RNA binding protein, fox-1 homolog (C. elegans) 1; Anti | ANTIBODIES | n/a |
GFS:P07098 | RNA binding protein, fox-1 homolog (C. elegans) 1; Protien | Protien | n/a |