Symbol: Name: ID: |
RASD1 RAS, dexamethasone-induced 1 GFS:4968 |
Gene name: | RASD1 |
Chromosome: | 17p11.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | DEXRAS1, AGS1 |
Name Aliases: | ras-related protein, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1270848 | Rat Genome Database ID: | RGD:619727 |
HGNC ID: | HGNC:15828 | RefSeq IDs: | NM_001199989 |
Entrez Gene ID: | 51655 | Ensembl Gene ID: | ENSG00000108551 |
VEGA IDs: | OTTHUMG00000059292 | UniProt ID: | Q9Y272 |
UCSC ID: | uc002gri.2 | OMIM ID: | 605550 |
Pubmed: | PMID10947988 | ||
CCDS IDs: | CCDSCCDS11185.1 |
Dexamethasone-induced Ras-related protein 1 is a protein that in humans is encoded by the RASD1 gene.
This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2011].
Function: Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65 (By similarity).
Products for RASD1 gene
Catalog | Product Name | Application | Company |
GFS:E04968 | RAS, dexamethasone-induced 1; ELISA kit | ELISA | n/a |
GFS:A04968 | RAS, dexamethasone-induced 1; Anti | ANTIBODIES | n/a |
GFS:P04968 | RAS, dexamethasone-induced 1; Protien | Protien | n/a |