Symbol: Name: ID: |
RANBP9 RAN binding protein 9 GFS:3233 |
Gene name: | RANBP9 |
Chromosome: | 6p23 |
Previous Symbols: | |
Previous Names: | |
Aliases: | RanBPM |
Name Aliases: | Ran Binding Protein in the Microtubule organizing center |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1928741 | Rat Genome Database ID: | |
HGNC ID: | HGNC:13727 | RefSeq IDs: | NM_005493 |
Entrez Gene ID: | 10048 | Ensembl Gene ID: | ENSG00000010017 |
VEGA IDs: | OTTHUMG00000015642 | UniProt ID: | Q96S59 |
UCSC ID: | uc003nbb.2 | OMIM ID: | 603854 |
Pubmed: | PMID9817760 | ||
CCDS IDs: | CCDSCCDS4529.1 |
Ran-binding protein 9 is a protein that in humans is encoded by the RANBP9 gene.
This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Involved in activation of androgen and glucocorticoid receptor in the presence of their cognate hormones. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.
Products for RANBP9 gene
Catalog | Product Name | Application | Company |
GFS:E03233 | RAN binding protein 9; ELISA kit | ELISA | n/a |
GFS:A03233 | RAN binding protein 9; Anti | ANTIBODIES | n/a |
GFS:P03233 | RAN binding protein 9; Protien | Protien | n/a |