Symbol: Name: ID: |
PRDM9 PR domain containing 9 GFS:3427 |
Gene name: | PRDM9 |
Chromosome: | 5p14.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | PFM6, ZNF899 |
Name Aliases: | PR-domain containing protein 9 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2384854 | Rat Genome Database ID: | RGD:1305247 |
HGNC ID: | HGNC:13994 | RefSeq IDs: | NM_020227 |
Entrez Gene ID: | 56979 | Ensembl Gene ID: | ENSG00000164256 |
VEGA IDs: | OTTHUMG00000161918 | UniProt ID: | Q9NQV7 |
UCSC ID: | uc003jgo.2 | OMIM ID: | 609760 |
Pubmed: | PMID10668202 | ||
CCDS IDs: | CCDSCCDS43307.1 |
The PR domain is a protein-protein interaction module of about 100 amino acids. PR domain-containing proteins, such as PRDM9, are often involved in transcriptional regulation (Jiang and Huang, 2000 [PubMed 10668202]).[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Histone methyltransferase that specifically trimethylates 'Lys-4' of histone H3 during meiotic prophase and is essential for proper meiotic progression. Does not have the ability to mono- and dimethylate 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes during early meiotic prophase (By similarity).
Products for PRDM9 gene
Catalog | Product Name | Application | Company |
GFS:E03427 | PR domain containing 9; ELISA kit | ELISA | n/a |
GFS:A03427 | PR domain containing 9; Anti | ANTIBODIES | n/a |
GFS:P03427 | PR domain containing 9; Protien | Protien | n/a |