Symbol: Name: ID: |
PHF5A PHD finger protein 5A GFS:6897 |
Gene name: | PHF5A |
Chromosome: | 22q13.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | MGC1346, SF3b14b, INI, bK223H9.2, Rds3, SAP14b |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2156864 | Rat Genome Database ID: | RGD:621555 |
HGNC ID: | HGNC:18000 | RefSeq IDs: | NM_032758 |
Entrez Gene ID: | 84844 | Ensembl Gene ID: | ENSG00000100410 |
VEGA IDs: | OTTHUMG00000150966 | UniProt ID: | Q7RTV0 |
UCSC ID: | uc003bab.2 | OMIM ID: | |
Pubmed: | PMID12054543 PMID 12234937 PMID 18076038 | ||
CCDS IDs: | CCDSCCDS14016.1 |
This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes. [provided by RefSeq, Jul 2008].
Function: Acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER-alpha. Also involved in pre-mRNA splicing.
Products for PHF5A gene
Catalog | Product Name | Application | Company |
GFS:E06897 | PHD finger protein 5A; ELISA kit | ELISA | n/a |
GFS:A06897 | PHD finger protein 5A; Anti | ANTIBODIES | n/a |
GFS:P06897 | PHD finger protein 5A; Protien | Protien | n/a |