Symbol: Name: ID: |
NPC2 Niemann-Pick disease, type C2 GFS:3852 |
Gene name: | NPC2 |
Chromosome: | 14q24.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | HE1, NP-C2, EDDM1 |
Name Aliases: | epididymal protein 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1915213 | Rat Genome Database ID: | RGD:628756 |
HGNC ID: | HGNC:14537 | RefSeq IDs: | NM_006432 |
Entrez Gene ID: | 10577 | Ensembl Gene ID: | ENSG00000119655 |
VEGA IDs: | UniProt ID: | P61916 | |
UCSC ID: | uc001xpy.2 | OMIM ID: | 601015 |
Pubmed: | PMID8418812 PMID 11125141 | ||
CCDS IDs: | CCDSCCDS32121.1 |
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May be involved in the regulation of the lipid composition of sperm membranes during the maturation in the epididymis (By similarity).
Products for NPC2 gene
Catalog | Product Name | Application | Company |
GFS:E03852 | Niemann-Pick disease, type C2; ELISA kit | ELISA | n/a |
GFS:A03852 | Niemann-Pick disease, type C2; Anti | ANTIBODIES | n/a |
GFS:P03852 | Niemann-Pick disease, type C2; Protien | Protien | n/a |