Symbol: Name: ID: |
NXT1 NTF2-like export factor 1 GFS:5047 |
Gene name: | NXT1 |
Chromosome: | 20p12-p11.2 |
Previous Symbols: | |
Previous Names: | NTX2-like export factor1 |
Aliases: | P15, MTR2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1929619 | Rat Genome Database ID: | RGD:1309327 |
HGNC ID: | HGNC:15913 | RefSeq IDs: | NM_013248 |
Entrez Gene ID: | 29107 | Ensembl Gene ID: | ENSG00000132661 |
VEGA IDs: | OTTHUMG00000032059 | UniProt ID: | Q9UKK6 |
UCSC ID: | uc002wsx.1 | OMIM ID: | 605811 |
Pubmed: | PMID10567585 PMID 11259602 | ||
CCDS IDs: | CCDSCCDS13150.1 |
NTF2-related export protein 1 is a protein that in humans is encoded by the NXT1 gene.
The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with THOC4 and THOC5.
Products for NXT1 gene
Catalog | Product Name | Application | Company |
GFS:E05047 | NTF2-like export factor 1; ELISA kit | ELISA | n/a |
GFS:A05047 | NTF2-like export factor 1; Anti | ANTIBODIES | n/a |
GFS:P05047 | NTF2-like export factor 1; Protien | Protien | n/a |