Symbol: Name: ID: |
NSFL1C NSFL1 (p97) cofactor (p47) GFS:5046 |
Gene name: | NSFL1C |
Chromosome: | 20p13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | dJ776F14.1, p47, UBXD10, UBX1, UBXN2C |
Name Aliases: | SHP1 homolog (S. cerevisiae), |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:3042273 | Rat Genome Database ID: | RGD:619952 |
HGNC ID: | HGNC:15912 | RefSeq IDs: | NM_016143 |
Entrez Gene ID: | 55968 | Ensembl Gene ID: | ENSG00000088833 |
VEGA IDs: | OTTHUMG00000031665 | UniProt ID: | Q9UNZ2 |
UCSC ID: | uc002wfc.2 | OMIM ID: | 606610 |
Pubmed: | PMID11042152 | ||
CCDS IDs: | CCDSCCDS13015.1 CCDS CCDS13016.1 CCDS CCDS13017.1 |
NSFL1 cofactor p47 is a protein that in humans is encoded by the NSFL1C gene.
N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, May 2011].
Function: Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity). Inhibits the activity of CTSL (in vitro).
Products for NSFL1C gene
Catalog | Product Name | Application | Company |
GFS:E05046 | NSFL1 (p97) cofactor (p47); ELISA kit | ELISA | n/a |
GFS:A05046 | NSFL1 (p97) cofactor (p47); Anti | ANTIBODIES | n/a |
GFS:P05046 | NSFL1 (p97) cofactor (p47); Protien | Protien | n/a |