Protein NDRG2 is a protein that in humans is encoded by the NDRG2 gene (NMYC downstrean-regulated gene 2).

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].
Function: May be involved in dendritic cell and neuron differentiation. May have anti-tumor activity