Symbol: Name: ID: |
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 GFS:4162 |
Gene name: | NOX5 |
Chromosome: | 15q22.31 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NOX5A, NOX5B |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:14874 | RefSeq IDs: | NM_001184779 |
Entrez Gene ID: | 79400 | Ensembl Gene ID: | ENSG00000137808 |
VEGA IDs: | OTTHUMG00000133320 | UniProt ID: | Q96PH1 |
UCSC ID: | uc002arp.1 | OMIM ID: | 606572 |
Pubmed: | PMID11483596 | ||
CCDS IDs: | CCDSCCDS32276.1 |
NADPH oxidase, EF-hand calcium binding domain 5, also known as NOX5, is a protein which in humans is encoded by the NOX5 gene.
NOX5 is a novel NADPH oxidase that generates superoxide and functions as a H+ channel in a Ca(2+)-dependent manner.[supplied by OMIM, Jul 2002].
Function: Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform 2 and isoform 5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin.
Products for NOX5 gene
Catalog | Product Name | Application | Company |
GFS:E04162 | NADPH oxidase, EF-hand calcium binding domain 5; ELISA kit | ELISA | n/a |
GFS:A04162 | NADPH oxidase, EF-hand calcium binding domain 5; Anti | ANTIBODIES | n/a |
GFS:P04162 | NADPH oxidase, EF-hand calcium binding domain 5; Protien | Protien | n/a |