Symbol: Name: ID: |
NAGS N-acetylglutamate synthase GFS:6890 |
Gene name: | NAGS |
Chromosome: | 17q21.31 |
Previous Symbols: | |
Previous Names: | |
Aliases: | AGAS, ARGA, NAT7 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2387600 | Rat Genome Database ID: | RGD:1565783 |
HGNC ID: | HGNC:17996 | RefSeq IDs: | NM_153006 |
Entrez Gene ID: | 162417 | Ensembl Gene ID: | ENSG00000161653 |
VEGA IDs: | UniProt ID: | Q8N159 | |
UCSC ID: | uc002ies.2 | OMIM ID: | 608300 |
Pubmed: | PMID15050968 PMID 12459178 | ||
CCDS IDs: | CCDSCCDS11473.1 |
The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Plays a role in the regulation of ureagenesis by producing variable amounts of N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity.
Products for NAGS gene
Catalog | Product Name | Application | Company |
GFS:E06890 | N-acetylglutamate synthase; ELISA kit | ELISA | n/a |
GFS:A06890 | N-acetylglutamate synthase; Anti | ANTIBODIES | n/a |
GFS:P06890 | N-acetylglutamate synthase; Protien | Protien | n/a |