Symbol: Name: ID: |
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 GFS:3844 |
Gene name: | NAALAD2 |
Chromosome: | 11q14.3-q21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NAALADASE2, NAADALASE2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919810 | Rat Genome Database ID: | RGD:1305872 |
HGNC ID: | HGNC:14526 | RefSeq IDs: | NM_005467 |
Entrez Gene ID: | 10003 | Ensembl Gene ID: | ENSG00000077616 |
VEGA IDs: | UniProt ID: | Q9Y3Q0 | |
UCSC ID: | uc001pdf.3 | OMIM ID: | 611636 |
Pubmed: | PMID10085079 | ||
CCDS IDs: | CCDSCCDS8288.1 |
This gene is a member of the N-acetylated alpha-linked acidic dipeptidase (NAALADase) gene family. The representative member of this family is the gene encoding human prostate-specific membrane antigen (PSM), which is a marker of prostatic carcinomas and is the first to be shown to possess NAALADase activity. NAALADase cleaves N-acetyl-L-aspartate-L-glutamate (NAAG), which is a neuropeptide expressed both in the central nervous systems and in the periphery and is thought to function as a neurotransmitter. The product of this gene is a type II integral membrane protein. Transient transfection of this gene confers both NAALADase and dipetidyl peptidase IV activities to mammalian cells. This gene is highly expressed in ovary and testis as well as within discrete brain areas. [provided by RefSeq, Jul 2008].
Function: Has N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Also exhibits a dipeptidyl-peptidase IV type activity. Inactivate the peptide neurotransmitter N-acetylaspartylglutamate.
Products for NAALAD2 gene
Catalog | Product Name | Application | Company |
GFS:E03844 | N-acetylated alpha-linked acidic dipeptidase 2; ELISA kit | ELISA | n/a |
GFS:A03844 | N-acetylated alpha-linked acidic dipeptidase 2; Anti | ANTIBODIES | n/a |
GFS:P03844 | N-acetylated alpha-linked acidic dipeptidase 2; Protien | Protien | n/a |