| Symbol: Name: ID: |
MCF2L MCF.2 cell line derived transforming sequence-like GFS:3884 |
| Gene name: | MCF2L |
| Chromosome: | 13q34 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | KIAA0362, DBS, OST, ARHGEF14 |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:103263 | Rat Genome Database ID: | RGD:619782 |
| HGNC ID: | HGNC:14576 | RefSeq IDs: | NM_001112732 |
| Entrez Gene ID: | 23263 | Ensembl Gene ID: | ENSG00000126217 |
| VEGA IDs: | OTTHUMG00000017377 | UniProt ID: | O15068 |
| UCSC ID: | uc001vsu.2 | OMIM ID: | 609499 |
| Pubmed: | PMID9205841 | ||
| CCDS IDs: | CCDSCCDS9527.2 CCDS CCDS45070.1 | ||
Guanine nucleotide exchange factor DBS is a protein that in humans is encoded by the MCF2L gene.
Function: Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.
Products for MCF2L gene
| Catalog | Product Name | Application | Company |
| GFS:E03884 | MCF.2 cell line derived transforming sequence-like; ELISA kit | ELISA | n/a |
| GFS:A03884 | MCF.2 cell line derived transforming sequence-like; Anti | ANTIBODIES | n/a |
| GFS:P03884 | MCF.2 cell line derived transforming sequence-like; Protien | Protien | n/a |
