Symbol: Name: ID: |
MGA MAX gene associated GFS:3445 |
Gene name: | MGA |
Chromosome: | 15q15 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0518, MAD5, MXD5, FLJ12634 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1352483 | Rat Genome Database ID: | RGD:1561597 |
HGNC ID: | HGNC:14010 | RefSeq IDs: | NM_001080541 |
Entrez Gene ID: | 23269 | Ensembl Gene ID: | ENSG00000174197 |
VEGA IDs: | UniProt ID: | Q8IWI9 | |
UCSC ID: | uc010ucy.1 | OMIM ID: | |
Pubmed: | |||
CCDS IDs: |
Function: Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor (By similarity).
Products for MGA gene
Catalog | Product Name | Application | Company |
GFS:E03445 | MAX gene associated; ELISA kit | ELISA | n/a |
GFS:A03445 | MAX gene associated; Anti | ANTIBODIES | n/a |
GFS:P03445 | MAX gene associated; Protien | Protien | n/a |