Symbol: Name: ID: |
LASS1 LAG1 homolog, ceramide synthase 1 GFS:3618 |
Gene name: | LASS1 |
Chromosome: | 19p12 |
Previous Symbols: | |
Previous Names: | longevity assurance (LAG1, S. cerevisiae) homolog 1, "LAG1 longevity assurance homolog 1 (S. cerevisiae)" |
Aliases: | LAG1, UOG1, CerS1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2136690 | Rat Genome Database ID: | RGD:1305974 |
HGNC ID: | HGNC:14253 | RefSeq IDs: | NM_021267 |
Entrez Gene ID: | 10715 | Ensembl Gene ID: | ENSG00000223802 |
VEGA IDs: | UniProt ID: | P27544 | |
UCSC ID: | uc002nkj.2 | OMIM ID: | 606919 |
Pubmed: | PMID9872981 PMID 2034669 | ||
CCDS IDs: | CCDSCCDS46020.1 CCDS CCDS46021.1 |
LAG1 longevity assurance homolog 1 is a protein that in humans is encoded by the LASS1 gene.
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1. [provided by RefSeq, Jul 2008].
Function: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner (By similarity).
Products for LASS1 gene
Catalog | Product Name | Application | Company |
GFS:E03618 | LAG1 homolog, ceramide synthase 1; ELISA kit | ELISA | n/a |
GFS:A03618 | LAG1 homolog, ceramide synthase 1; Anti | ANTIBODIES | n/a |
GFS:P03618 | LAG1 homolog, ceramide synthase 1; Protien | Protien | n/a |