| Symbol: Name: ID: |
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 GFS:7005 |
| Gene name: | KHDRBS1 |
| Chromosome: | 1p32 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | Sam68, p62, FLJ34027 |
| Name Aliases: | GAP-associated tyrosine phosphoprotein p62 (Sam68) |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:893579 | Rat Genome Database ID: | RGD:621459 |
| HGNC ID: | HGNC:18116 | RefSeq IDs: | NM_006559 |
| Entrez Gene ID: | 10657 | Ensembl Gene ID: | ENSG00000121774 |
| VEGA IDs: | OTTHUMG00000003921 | UniProt ID: | Q07666 |
| UCSC ID: | uc001bub.2 | OMIM ID: | 602489 |
| Pubmed: | PMID1374686 PMID 10564820 | ||
| CCDS IDs: | CCDSCCDS350.1 | ||
KH domain-containing, RNA-binding, signal transduction-associated protein 1 is a protein that in humans is encoded by the KHDRBS1 gene.
Function: Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export
Function: Isoform 3, which is expressed in growth-arrested cells only, inhibits S phase.
Products for KHDRBS1 gene
| Catalog | Product Name | Application | Company |
| GFS:E07005 | KH domain containing, RNA binding, signal transduction associated 1; ELISA kit | ELISA | n/a |
| GFS:A07005 | KH domain containing, RNA binding, signal transduction associated 1; Anti | ANTIBODIES | n/a |
| GFS:P07005 | KH domain containing, RNA binding, signal transduction associated 1; Protien | Protien | n/a |
