Symbol: Name: ID: |
HNF1A HNF1 homeobox A GFS:1471 |
Gene name: | HNF1A |
Chromosome: | 12q24.31 |
Previous Symbols: | MODY3, TCF1 |
Previous Names: | transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor |
Aliases: | HNF1, LFB1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98504 | Rat Genome Database ID: | RGD:3828 |
HGNC ID: | HGNC:11621 | RefSeq IDs: | NM_000545 |
Entrez Gene ID: | 6927 | Ensembl Gene ID: | ENSG00000135100 |
VEGA IDs: | OTTHUMG00000151015 | UniProt ID: | P20823 |
UCSC ID: | uc001tzg.2 | OMIM ID: | 142410 |
Pubmed: | PMID1535333 PMID 7795649 | ||
CCDS IDs: | CCDSCCDS9209.1 |
HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A, is a human gene. The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.
Products for HNF1A gene
Catalog | Product Name | Application | Company |
GFS:E01471 | HNF1 homeobox A; ELISA kit | ELISA | n/a |
GFS:A01471 | HNF1 homeobox A; Anti | ANTIBODIES | n/a |
GFS:P01471 | HNF1 homeobox A; Protien | Protien | n/a |