Symbol: Name: ID: |
GULP1 GULP, engulfment adaptor PTB domain containing 1 GFS:7493 |
Gene name: | GULP1 |
Chromosome: | 2q32.3-q33 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CED6, CED-6, GULP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1920407 | Rat Genome Database ID: | RGD:1306380 |
HGNC ID: | HGNC:18649 | RefSeq IDs: | NM_016315 |
Entrez Gene ID: | 51454 | Ensembl Gene ID: | ENSG00000144366 |
VEGA IDs: | OTTHUMG00000132647 | UniProt ID: | Q9UBP9 |
UCSC ID: | uc002uqf.2 | OMIM ID: | 608165 |
Pubmed: | PMID11729193 | ||
CCDS IDs: | CCDSCCDS2295.1 |
The prompt clearance of cells undergoing apoptosis is critical during embryonic development, normal tissue turnover, inflammation, and autoimmunity. CED6 is an evolutionarily conserved adaptor protein required for efficient engulfment of apoptotic cells by phagocytes.[supplied by OMIM, Apr 2004].
Function: May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
Products for GULP1 gene
Catalog | Product Name | Application | Company |
GFS:E07493 | GULP, engulfment adaptor PTB domain containing 1; ELISA kit | ELISA | n/a |
GFS:A07493 | GULP, engulfment adaptor PTB domain containing 1; Anti | ANTIBODIES | n/a |
GFS:P07493 | GULP, engulfment adaptor PTB domain containing 1; Protien | Protien | n/a |