Symbol: Name: ID: |
GIGYF2 GRB10 interacting GYF protein 2 GFS:1769 |
Gene name: | GIGYF2 |
Chromosome: | 2q37.1 |
Previous Symbols: | PERQ2, PERQ3, TNRC15, PARK11 |
Previous Names: | PERQ amino acid rich, with GYF domain 2, "PERQ amino acid rich, with GYF domain 3", "trinucleotide repeat containing 15", "Parkinson disease (autosomal recessive, early onset) 11" |
Aliases: | KIAA0642, GYF2 |
Name Aliases: | GYF domain containing 2 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2138584 | Rat Genome Database ID: | |
HGNC ID: | HGNC:11960 | RefSeq IDs: | NM_001103146 |
Entrez Gene ID: | 26058 | Ensembl Gene ID: | ENSG00000204120 |
VEGA IDs: | OTTHUMG00000153237 | UniProt ID: | Q6Y7W6 |
UCSC ID: | uc002vtk.3 | OMIM ID: | 612003 |
Pubmed: | PMID9225980 PMID 9734811 PMID 12771153 PMID 18358451 | ||
CCDS IDs: | CCDSCCDS33401.1 CCDS CCDS46542.1 CCDS CCDS46543.1 |
PERQ amino acid-rich with GYF domain-containing protein 2 is a protein that in humans is encoded by the GIGYF2 gene. The protein encoded by this gene interacts with GRB10 and may be involved in the regulation of tyrosine kinase receptor signaling. This gene contains CAG repeats, and the encoded protein contains stretches glutamine and glutamic acid residues. Defects in this gene are a cause of Parkinson disease type 11 (PARK11). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors.
Products for GIGYF2 gene
Catalog | Product Name | Application | Company |
GFS:E01769 | GRB10 interacting GYF protein 2; ELISA kit | ELISA | n/a |
GFS:A01769 | GRB10 interacting GYF protein 2; Anti | ANTIBODIES | n/a |
GFS:P01769 | GRB10 interacting GYF protein 2; Protien | Protien | n/a |