Symbol: Name: ID: |
GFRA4 GDNF family receptor alpha 4 GFS:3297 |
Gene name: | GFRA4 |
Chromosome: | 20p13-p12 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | persephin receptor |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1341873 | Rat Genome Database ID: | RGD:620503 |
HGNC ID: | HGNC:13821 | RefSeq IDs: | NM_022139 |
Entrez Gene ID: | 64096 | Ensembl Gene ID: | ENSG00000125861 |
VEGA IDs: | OTTHUMG00000031748 | UniProt ID: | Q9GZZ7 |
UCSC ID: | uc002win.2 | OMIM ID: | |
Pubmed: | PMID10958791 PMID 15225646 | ||
CCDS IDs: | CCDSCCDS13055.1 CCDS CCDS13056.1 |
The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
Function: Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
Products for GFRA4 gene
Catalog | Product Name | Application | Company |
GFS:E03297 | GDNF family receptor alpha 4; ELISA kit | ELISA | n/a |
GFS:A03297 | GDNF family receptor alpha 4; Anti | ANTIBODIES | n/a |
GFS:P03297 | GDNF family receptor alpha 4; Protien | Protien | n/a |