Symbol: Name: ID: |
GPRC6A G protein-coupled receptor, family C, group 6, member A GFS:7359 |
Gene name: | GPRC6A |
Chromosome: | 6q22.31 |
Previous Symbols: | |
Previous Names: | |
Aliases: | bA86F4.3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2429498 | Rat Genome Database ID: | RGD:735077 |
HGNC ID: | HGNC:18510 | RefSeq IDs: | NM_148963 |
Entrez Gene ID: | 222545 | Ensembl Gene ID: | ENSG00000173612 |
VEGA IDs: | OTTHUMG00000015447 | UniProt ID: | Q5T6X5 |
UCSC ID: | uc003pxj.1 | OMIM ID: | 613572 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS5112.1 |
G-protein coupled receptor family C group 6 member A is a protein that in humans is encoded by the GPRC6A gene.
Members of family C of the G protein-coupled receptor (GPCR) superfamily, such as GPRC6A, are characterized by an evolutionarily conserved amino acid-sensing motif linked to an intramembranous 7-transmembrane loop region. Several members of GPCR family C, including GPRC6A, also have a long N-terminal domain (summary by Pi et al., 2005 [PubMed 16199532]).[supplied by OMIM, Nov 2010]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritionnal and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids.
Products for GPRC6A gene
Catalog | Product Name | Application | Company |
GFS:E07359 | G protein-coupled receptor, family C, group 6, member A; ELISA kit | ELISA | n/a |
GFS:A07359 | G protein-coupled receptor, family C, group 6, member A; Anti | ANTIBODIES | n/a |
GFS:P07359 | G protein-coupled receptor, family C, group 6, member A; Protien | Protien | n/a |