Symbol: Name: ID: |
GTSE1 G-2 and S-phase expressed 1 GFS:3209 |
Gene name: | GTSE1 |
Chromosome: | 22q13.2-q13.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | GTSE-1, B99 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1352755 | Rat Genome Database ID: | RGD:1563164 |
HGNC ID: | HGNC:13698 | RefSeq IDs: | NM_016426 |
Entrez Gene ID: | 51512 | Ensembl Gene ID: | ENSG00000075218 |
VEGA IDs: | OTTHUMG00000150486 | UniProt ID: | Q9NYZ3 |
UCSC ID: | uc011aqy.1 | OMIM ID: | 607477 |
Pubmed: | PMID10974554 PMID 10984615 PMID 12750368 | ||
CCDS IDs: | CCDSCCDS14074.2 |
G2 and S phase-expressed protein 1 is an enzyme that in humans is encoded by the GTSE1 gene.
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.
Products for GTSE1 gene
Catalog | Product Name | Application | Company |
GFS:E03209 | G-2 and S-phase expressed 1; ELISA kit | ELISA | n/a |
GFS:A03209 | G-2 and S-phase expressed 1; Anti | ANTIBODIES | n/a |
GFS:P03209 | G-2 and S-phase expressed 1; Protien | Protien | n/a |