Symbol: Name: ID: |
FEV FEV (ETS oncogene family) GFS:7407 |
Gene name: | FEV |
Chromosome: | 2q36 |
Previous Symbols: | |
Previous Names: | FEV (fifth Ewing variant) |
Aliases: | Pet-1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2449712 | Rat Genome Database ID: | RGD:628860 |
HGNC ID: | HGNC:18562 | RefSeq IDs: | NM_017521 |
Entrez Gene ID: | 54738 | Ensembl Gene ID: | ENSG00000163497 |
VEGA IDs: | OTTHUMG00000133080 | UniProt ID: | Q99581 |
UCSC ID: | uc002vji.1 | OMIM ID: | 607150 |
Pubmed: | PMID9121764 | ||
CCDS IDs: | CCDSCCDS2428.1 |
This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Functions as a transcriptional regulator. According to PubMed:12761502, it functions as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth.
Products for FEV gene
Catalog | Product Name | Application | Company |
GFS:E07407 | FEV (ETS oncogene family); ELISA kit | ELISA | n/a |
GFS:A07407 | FEV (ETS oncogene family); Anti | ANTIBODIES | n/a |
GFS:P07407 | FEV (ETS oncogene family); Protien | Protien | n/a |