| Symbol: Name: ID: |
EMG1 EMG1 nucleolar protein homolog (S. cerevisiae) GFS:5998 |
| Gene name: | EMG1 |
| Chromosome: | 12p13 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | C2F, NEP1, Grcc2f |
| Name Aliases: | |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1315195 | Rat Genome Database ID: | RGD:1307665 |
| HGNC ID: | HGNC:16912 | RefSeq IDs: | NM_006331 |
| Entrez Gene ID: | 10436 | Ensembl Gene ID: | ENSG00000126749 |
| VEGA IDs: | UniProt ID: | Q92979 | |
| UCSC ID: | uc001qsh.3 | OMIM ID: | 611531 |
| Pubmed: | PMID9074930 PMID 11935223 | ||
| CCDS IDs: | |||
Probable ribosome biogenesis protein NEP1 is a protein that in humans is encoded by the EMG1 gene.
This gene encodes an essential, conserved eukaryotic protein involved in ribosome biogenesis. In yeast, the related protein is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome.[provided by RefSeq, May 2010].
Function: Involved in 40S ribosomal subunit biogenesis and 18S rRNA processing. Specifically catalyzes the N1-methylation of pseudouridine at position 1248 (Psi1248) in 18S rRNA. Thus, appears to be the methyltransferase involved in the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) in position 1248 in 18S rRNA. Is not able to methylate uridine at this position.
Products for EMG1 gene
| Catalog | Product Name | Application | Company |
| GFS:E05998 | EMG1 nucleolar protein homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
| GFS:A05998 | EMG1 nucleolar protein homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
| GFS:P05998 | EMG1 nucleolar protein homolog (S. cerevisiae); Protien | Protien | n/a |
