Symbol: Name: ID: |
ERC1 ELKS/RAB6-interacting/CAST family member 1 GFS:6166 |
Gene name: | ERC1 |
Chromosome: | 12p13.3 |
Previous Symbols: | RAB6IP2 |
Previous Names: | RAB6 interacting protein 2 |
Aliases: | ELKS, KIAA1081, CAST2, MGC12974 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2151013 | Rat Genome Database ID: | RGD:628733 |
HGNC ID: | HGNC:17072 | RefSeq IDs: | NR_027949 |
Entrez Gene ID: | 23085 | Ensembl Gene ID: | ENSG00000082805 |
VEGA IDs: | OTTHUMG00000130138 | UniProt ID: | Q8IUD2 |
UCSC ID: | uc001qjb.2 | OMIM ID: | 607127 |
Pubmed: | PMID10697956 PMID 11929610 | ||
CCDS IDs: | CCDSCCDS8508.1 |
ELKS/RAB6-interacting/CAST family member 1 is a protein that in humans is encoded by the ERC1 gene.
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function: Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport.
Products for ERC1 gene
Catalog | Product Name | Application | Company |
GFS:E06166 | ELKS/RAB6-interacting/CAST family member 1; ELISA kit | ELISA | n/a |
GFS:A06166 | ELKS/RAB6-interacting/CAST family member 1; Anti | ANTIBODIES | n/a |
GFS:P06166 | ELKS/RAB6-interacting/CAST family member 1; Protien | Protien | n/a |