Symbol: Name: ID: |
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 GFS:4678 |
Gene name: | DNAJC6 |
Chromosome: | 1p31.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0473 |
Name Aliases: | auxilin |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919935 | Rat Genome Database ID: | RGD:1309900 |
HGNC ID: | HGNC:15469 | RefSeq IDs: | NM_014787 |
Entrez Gene ID: | 9829 | Ensembl Gene ID: | ENSG00000116675 |
VEGA IDs: | OTTHUMG00000009066 | UniProt ID: | O75061 |
UCSC ID: | uc001dcd.1 | OMIM ID: | 608375 |
Pubmed: | PMID9455484 PMID 11147971 | ||
CCDS IDs: | CCDSCCDS30739.1 |
Putative tyrosine-protein phosphatase auxilin is an enzyme that in humans is encoded by the DNAJC6 gene.
DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008].
Function: Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles (By similarity).
Products for DNAJC6 gene
Catalog | Product Name | Application | Company |
GFS:E04678 | DnaJ (Hsp40) homolog, subfamily C, member 6; ELISA kit | ELISA | n/a |
GFS:A04678 | DnaJ (Hsp40) homolog, subfamily C, member 6; Anti | ANTIBODIES | n/a |
GFS:P04678 | DnaJ (Hsp40) homolog, subfamily C, member 6; Protien | Protien | n/a |