Symbol: Name: ID: |
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 GFS:1623 |
Gene name: | DNAJA3 |
Chromosome: | 16p13.3 |
Previous Symbols: | TID1 |
Previous Names: | |
Aliases: | hTid-1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1933786 | Rat Genome Database ID: | RGD:1306527 |
HGNC ID: | HGNC:11808 | RefSeq IDs: | NM_001135110 |
Entrez Gene ID: | 9093 | Ensembl Gene ID: | ENSG00000103423 |
VEGA IDs: | OTTHUMG00000129470 | UniProt ID: | Q96EY1 |
UCSC ID: | uc002cwk.2 | OMIM ID: | 608382 |
Pubmed: | PMID9683573 | ||
CCDS IDs: | CCDSCCDS10515.1 CCDS CCDS45400.1 |
DnaJ homolog subfamily A member 3, mitochondrial is a protein that in humans is encoded by the DNAJA3 gene. DNAJA3 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins. For background information on the DNAJ family, see MIM 608375.[supplied by OMIM].
Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity.
Products for DNAJA3 gene
Catalog | Product Name | Application | Company |
GFS:E01623 | DnaJ (Hsp40) homolog, subfamily A, member 3; ELISA kit | ELISA | n/a |
GFS:A01623 | DnaJ (Hsp40) homolog, subfamily A, member 3; Anti | ANTIBODIES | n/a |
GFS:P01623 | DnaJ (Hsp40) homolog, subfamily A, member 3; Protien | Protien | n/a |