Symbol: Name: ID: |
DCLRE1A DNA cross-link repair 1A GFS:6609 |
Gene name: | DCLRE1A |
Chromosome: | 10q25.1 |
Previous Symbols: | |
Previous Names: | DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae) |
Aliases: | SNM1, PSO2, KIAA0086, hSNM1 |
Name Aliases: | PSO2 homolog (S. cerevisiae) |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1930042 | Rat Genome Database ID: | RGD:1306156 |
HGNC ID: | HGNC:17660 | RefSeq IDs: | NM_014881 |
Entrez Gene ID: | 9937 | Ensembl Gene ID: | ENSG00000198924 |
VEGA IDs: | OTTHUMG00000019077 | UniProt ID: | Q6PJP8 |
UCSC ID: | uc001law.2 | OMIM ID: | 609682 |
Pubmed: | PMID9806498 PMID 17804464 | ||
CCDS IDs: | CCDSCCDS7584.1 |
DNA cross-link repair 1A protein is a protein that in humans is encoded by the DCLRE1A gene.
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1A is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.
Products for DCLRE1A gene
Catalog | Product Name | Application | Company |
GFS:E06609 | DNA cross-link repair 1A; ELISA kit | ELISA | n/a |
GFS:A06609 | DNA cross-link repair 1A; Anti | ANTIBODIES | n/a |
GFS:P06609 | DNA cross-link repair 1A; Protien | Protien | n/a |