Symbol: Name: ID: |
DCP1A DCP1 decapping enzyme homolog A (S. cerevisiae) GFS:7551 |
Gene name: | DCP1A |
Chromosome: | 3p21.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | HSA275986, SMIF, SMAD4IP1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1923151 | Rat Genome Database ID: | RGD:1561298 |
HGNC ID: | HGNC:18714 | RefSeq IDs: | NM_018403 |
Entrez Gene ID: | 55802 | Ensembl Gene ID: | ENSG00000162290 |
VEGA IDs: | OTTHUMG00000158193 | UniProt ID: | Q9NPI6 |
UCSC ID: | uc003dgs.3 | OMIM ID: | 607010 |
Pubmed: | |||
CCDS IDs: |
mRNA-decapping enzyme 1A is a protein that in humans is encoded by the DCP1A gene.
Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.
Products for DCP1A gene
Catalog | Product Name | Application | Company |
GFS:E07551 | DCP1 decapping enzyme homolog A (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A07551 | DCP1 decapping enzyme homolog A (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P07551 | DCP1 decapping enzyme homolog A (S. cerevisiae); Protien | Protien | n/a |