Symbol: Name: ID: |
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) GFS:7070 |
Gene name: | DCUN1D1 |
Chromosome: | 3q26.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | RP42, SCRO, DCUN1L1, Tes3, SCCRO |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2150386 | Rat Genome Database ID: | RGD:1309668 |
HGNC ID: | HGNC:18184 | RefSeq IDs: | NM_020640 |
Entrez Gene ID: | 54165 | Ensembl Gene ID: | ENSG00000043093 |
VEGA IDs: | OTTHUMG00000158314 | UniProt ID: | Q96GG9 |
UCSC ID: | uc003fld.1 | OMIM ID: | 605905 |
Pubmed: | PMID10777668 PMID 15988528 | ||
CCDS IDs: | CCDSCCDS3240.1 |
DCN1-like protein 1 is a protein that in humans is encoded by the DCUN1D1 gene.
Function: Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 mullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression (By similarity).
Products for DCUN1D1 gene
Catalog | Product Name | Application | Company |
GFS:E07070 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A07070 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P07070 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae); Protien | Protien | n/a |