| Symbol: Name: ID: |
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like GFS:5976 |
| Gene name: | CTDSPL |
| Chromosome: | 3p21.3 |
| Previous Symbols: | C3orf8 |
| Previous Names: | chromosome 3 open reading frame 8 |
| Aliases: | HYA22, SCP3, PSR1, RBSP3 |
| Name Aliases: | small CTD phosphatase 3, |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1916524 | Rat Genome Database ID: | RGD:1304841 |
| HGNC ID: | HGNC:16890 | RefSeq IDs: | NM_001008392 |
| Entrez Gene ID: | 10217 | Ensembl Gene ID: | ENSG00000144677 |
| VEGA IDs: | OTTHUMG00000155942 | UniProt ID: | O15194 |
| UCSC ID: | uc003chg.2 | OMIM ID: | 608592 |
| Pubmed: | PMID9179494 PMID 12543795 | ||
| CCDS IDs: | CCDSCCDS33734.1 CCDS CCDS33735.1 | ||
CTD small phosphatase-like protein is an enzyme that in humans is encoded by the CTDSPL gene.
Function: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Products for CTDSPL gene
| Catalog | Product Name | Application | Company |
| GFS:E05976 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like; ELISA kit | ELISA | n/a |
| GFS:A05976 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like; Anti | ANTIBODIES | n/a |
| GFS:P05976 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like; Protien | Protien | n/a |
