Symbol: Name: ID: |
CRTC1 CREB regulated transcription coactivator 1 GFS:5188 |
Gene name: | CRTC1 |
Chromosome: | 19p13 |
Previous Symbols: | MECT1 |
Previous Names: | mucoepidermoid carcinoma translocated 1 |
Aliases: | KIAA0616, FLJ14027, TORC1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2142523 | Rat Genome Database ID: | |
HGNC ID: | HGNC:16062 | RefSeq IDs: | NM_001098482 |
Entrez Gene ID: | 23373 | Ensembl Gene ID: | ENSG00000105662 |
VEGA IDs: | UniProt ID: | Q6UUV9 | |
UCSC ID: | uc010ebv.2 | OMIM ID: | 607536 |
Pubmed: | PMID12539049 PMID 14536081 PMID 14506290 | ||
CCDS IDs: | CCDSCCDS32963.1 CCDS CCDS42525.1 |
CREB-regulated transcription coactivator 1 (CRTC1), previously referred to as TORC1
Function: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses (By imilarity).
Products for CRTC1 gene
Catalog | Product Name | Application | Company |
GFS:E05188 | CREB regulated transcription coactivator 1; ELISA kit | ELISA | n/a |
GFS:A05188 | CREB regulated transcription coactivator 1; Anti | ANTIBODIES | n/a |
GFS:P05188 | CREB regulated transcription coactivator 1; Protien | Protien | n/a |