Symbol: Name: ID: |
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion GFS:4929 |
Gene name: | CHRFAM7A |
Chromosome: | 15q13.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | D-10, CHRNA7-DR1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | Rat Genome Database ID: | ||
HGNC ID: | HGNC:15781 | RefSeq IDs: | NM_139320 |
Entrez Gene ID: | 89832 | Ensembl Gene ID: | ENSG00000166664 |
VEGA IDs: | UniProt ID: | Q494W8 | |
UCSC ID: | uc001zdt.1 | OMIM ID: | 609756 |
Pubmed: | PMID11829490 | ||
CCDS IDs: | CCDSCCDS32184.1 CCDS CCDS42008.1 |
CHRNA7-FAM7A fusion protein is a protein that in humans is encoded by the CHRFAM7A gene.
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008].
Products for CHRFAM7A gene
Catalog | Product Name | Application | Company |
GFS:E04929 | CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion; ELISA kit | ELISA | n/a |
GFS:A04929 | CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion; Anti | ANTIBODIES | n/a |
GFS:P04929 | CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion; Protien | Protien | n/a |