Symbol: Name: ID: |
CRCP CGRP receptor component GFS:6789 |
Gene name: | CRCP |
Chromosome: | 7q11.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CGRP-RCP, RCP, RCP9 |
Name Aliases: | calcitonin gene-related peptide-receptor component protein |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1100818 | Rat Genome Database ID: | RGD:620753 |
HGNC ID: | HGNC:17888 | RefSeq IDs: | NM_001040647 |
Entrez Gene ID: | 27297 | Ensembl Gene ID: | ENSG00000241258 |
VEGA IDs: | OTTHUMG00000129519 | UniProt ID: | O75575 |
UCSC ID: | uc011kdw.1 | OMIM ID: | 606121 |
Pubmed: | PMID8622957 PMID 10067875 PMID 12482973 | ||
CCDS IDs: | CCDSCCDS5532.1 CCDS CCDS47599.1 CCDS CCDS47600.1 |
DNA-directed RNA polymerase III subunit RPC9 is an enzyme that in humans is encoded by the CRCP gene.
This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Function: Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
Products for CRCP gene
Catalog | Product Name | Application | Company |
GFS:E06789 | CGRP receptor component; ELISA kit | ELISA | n/a |
GFS:A06789 | CGRP receptor component; Anti | ANTIBODIES | n/a |
GFS:P06789 | CGRP receptor component; Protien | Protien | n/a |