Symbol: Name: ID: |
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase GFS:6626 |
Gene name: | CDIPT |
Chromosome: | 16p12.1 |
Previous Symbols: | |
Previous Names: | CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) |
Aliases: | PIS1, PIS |
Name Aliases: | phosphatidylinositol synthase |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:105491 | Rat Genome Database ID: | RGD:620576 |
HGNC ID: | HGNC:1769 | RefSeq IDs: | NM_006319 |
Entrez Gene ID: | 10423 | Ensembl Gene ID: | ENSG00000103502 |
VEGA IDs: | OTTHUMG00000132108 | UniProt ID: | O14735 |
UCSC ID: | uc002dum.2 | OMIM ID: | 605893 |
Pubmed: | PMID9407135 | ||
CCDS IDs: | CCDSCCDS10657.1 |
CDP-diacylglycerol--inositol 3-phosphatidyltransferase is an enzyme that in humans is encoded by the CDIPT gene.
Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus. [provided by RefSeq, Jul 2008].
Function: Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme.
Products for CDIPT gene
Catalog | Product Name | Application | Company |
GFS:E06626 | CDP-diacylglycerol--inositol 3-phosphatidyltransferase; ELISA kit | ELISA | n/a |
GFS:A06626 | CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Anti | ANTIBODIES | n/a |
GFS:P06626 | CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Protien | Protien | n/a |