Symbol: Name: ID: |
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon GFS:7226 |
Gene name: | CEBPE |
Chromosome: | 14q11.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CRP1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:103572 | Rat Genome Database ID: | RGD:2329 |
HGNC ID: | HGNC:1836 | RefSeq IDs: | NM_001805 |
Entrez Gene ID: | 1053 | Ensembl Gene ID: | |
VEGA IDs: | OTTHUMG00000028719 | UniProt ID: | Q15744 |
UCSC ID: | uc001wiv.1 | OMIM ID: | 600749 |
Pubmed: | PMID8661101 | ||
CCDS IDs: | CCDSCCDS9589.1 |
CCAAT/enhancer binding protein (C/EBP), epsilon, also known as CEBPE and CHOP, is a type of ccaat-enhancer-binding protein. CEBPE is its human gene. It is pro-apoptotic.
The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.
Products for CEBPE gene
Catalog | Product Name | Application | Company |
GFS:E07226 | CCAAT/enhancer binding protein (C/EBP), epsilon; ELISA kit | ELISA | n/a |
GFS:A07226 | CCAAT/enhancer binding protein (C/EBP), epsilon; Anti | ANTIBODIES | n/a |
GFS:P07226 | CCAAT/enhancer binding protein (C/EBP), epsilon; Protien | Protien | n/a |