Symbol: Name: ID: |
BANP BTG3 associated nuclear protein GFS:3031 |
Gene name: | BANP |
Chromosome: | 16q24 |
Previous Symbols: | |
Previous Names: | |
Aliases: | SMARBP1, SMAR1, FLJ20538, DKFZp761H172, FLJ10177, BEND1 |
Name Aliases: | BEN domain containing 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1889023 | Rat Genome Database ID: | RGD:1307464 |
HGNC ID: | HGNC:13450 | RefSeq IDs: | NM_001173539 |
Entrez Gene ID: | 54971 | Ensembl Gene ID: | ENSG00000172530 |
VEGA IDs: | OTTHUMG00000137678 | UniProt ID: | Q8N9N5 |
UCSC ID: | uc002fkp.2 | OMIM ID: | 611564 |
Pubmed: | PMID10940556 PMID 10950932 | ||
CCDS IDs: | CCDSCCDS10966.2 CCDS CCDS42215.1 |
Protein BANP is a protein that in humans is encoded by the BANP gene.
This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
Function: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).
Products for BANP gene
Catalog | Product Name | Application | Company |
GFS:E03031 | BTG3 associated nuclear protein; ELISA kit | ELISA | n/a |
GFS:A03031 | BTG3 associated nuclear protein; Anti | ANTIBODIES | n/a |
GFS:P03031 | BTG3 associated nuclear protein; Protien | Protien | n/a |