Symbol: Name: ID: |
BRF1 BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) GFS:1408 |
Gene name: | BRF1 |
Chromosome: | 14q |
Previous Symbols: | TAF3B2, TAF3C, GTF3B |
Previous Names: | TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 2 |
Aliases: | TFIIIB90, BRF, hBRF |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919558 | Rat Genome Database ID: | RGD:1311158 |
HGNC ID: | HGNC:11551 | RefSeq IDs: | NM_001519 |
Entrez Gene ID: | 2972 | Ensembl Gene ID: | ENSG00000185024 |
VEGA IDs: | OTTHUMG00000029884 | UniProt ID: | Q92994 |
UCSC ID: | uc001yqp.2 | OMIM ID: | 604902 |
Pubmed: | PMID7624363 PMID 8943358 | ||
CCDS IDs: | CCDSCCDS10001.1 CCDS CCDS42001.1 |
Transcription factor IIIB 90 kDa subunit is a protein that in humans is encoded by the BRF1 gene. This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq].
General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.
Products for BRF1 gene
Catalog | Product Name | Application | Company |
GFS:E01408 | BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A01408 | BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P01408 | BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae); Protien | Protien | n/a |