Symbol: Name: ID: |
BMI1 BMI1 polycomb ring finger oncogene GFS:582 |
Gene name: | BMI1 |
Chromosome: | 10p13 |
Previous Symbols: | PCGF4 |
Previous Names: | polycomb group ring finger 4, "B lymphoma Mo-MLV insertion region 1 homolog (mouse)" |
Aliases: | RNF51 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88174 | Rat Genome Database ID: | RGD:1307403 |
HGNC ID: | HGNC:1066 | RefSeq IDs: | NM_005180 |
Entrez Gene ID: | 648 | Ensembl Gene ID: | ENSG00000168283 |
VEGA IDs: | OTTHUMG00000017807 | UniProt ID: | P35226 |
UCSC ID: | uc009xkg.2 | OMIM ID: | 164831 |
Pubmed: | PMID8268912 | ||
CCDS IDs: | CCDSCCDS7138.1 |
BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1 gene.
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain thetranscriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2
Products for BMI1 gene
Catalog | Product Name | Application | Company |
GFS:E00582 | BMI1 polycomb ring finger oncogene; ELISA kit | ELISA | n/a |
GFS:A00582 | BMI1 polycomb ring finger oncogene; Anti | ANTIBODIES | n/a |
GFS:P00582 | BMI1 polycomb ring finger oncogene; Protien | Protien | n/a |