Symbol: Name: ID: |
BLK B lymphoid tyrosine kinase GFS:497 |
Gene name: | BLK |
Chromosome: | 8p23-p22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | MGC10442 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88169 | Rat Genome Database ID: | RGD:1308859 |
HGNC ID: | HGNC:1057 | RefSeq IDs: | NM_001715 |
Entrez Gene ID: | 640 | Ensembl Gene ID: | ENSG00000136573 |
VEGA IDs: | OTTHUMG00000090729 | UniProt ID: | P51451 |
UCSC ID: | uc003wty.2 | OMIM ID: | 191305 |
Pubmed: | PMID7845672 | ||
CCDS IDs: | CCDSCCDS5982.1 |
Tyrosine-protein kinase BLK also known as B lymphocyte kinase is an enzyme that in humans is encoded by the BLK gene.This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Modulator of beta-cells function, acting through the up-regulation of PDX1 and NKX6-1 and consequent stimulation of insulin secretion in response to glucose
Products for BLK gene
Catalog | Product Name | Application | Company |
GFS:E00497 | B lymphoid tyrosine kinase; ELISA kit | ELISA | n/a |
GFS:A00497 | B lymphoid tyrosine kinase; Anti | ANTIBODIES | n/a |
GFS:P00497 | B lymphoid tyrosine kinase; Protien | Protien | n/a |