Symbol: Name: ID: |
BANK1 B-cell scaffold protein with ankyrin repeats 1 GFS:7106 |
Gene name: | BANK1 |
Chromosome: | 4q23 |
Previous Symbols: | |
Previous Names: | |
Aliases: | BANK, FLJ20706 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2442120 | Rat Genome Database ID: | RGD:1564639 |
HGNC ID: | HGNC:18233 | RefSeq IDs: | NM_001083907 |
Entrez Gene ID: | 55024 | Ensembl Gene ID: | ENSG00000153064 |
VEGA IDs: | UniProt ID: | Q8NDB2 | |
UCSC ID: | uc003hvy.3 | OMIM ID: | 610292 |
Pubmed: | PMID11782428 | ||
CCDS IDs: | CCDSCCDS34038.1 CCDS CCDS47115.1 CCDS CCDS47116.1 |
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
Function: Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2.
Products for BANK1 gene
Catalog | Product Name | Application | Company |
GFS:E07106 | B-cell scaffold protein with ankyrin repeats 1; ELISA kit | ELISA | n/a |
GFS:A07106 | B-cell scaffold protein with ankyrin repeats 1; Anti | ANTIBODIES | n/a |
GFS:P07106 | B-cell scaffold protein with ankyrin repeats 1; Protien | Protien | n/a |