Symbol: Name: ID: |
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F GFS:5919 |
Gene name: | ATP6V1F |
Chromosome: | 7q32.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | ATP6S14, VATF, Vma7 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1913394 | Rat Genome Database ID: | RGD:621552 |
HGNC ID: | HGNC:16832 | RefSeq IDs: | NM_001198909 |
Entrez Gene ID: | 9296 | Ensembl Gene ID: | ENSG00000128524 |
VEGA IDs: | OTTHUMG00000158365 | UniProt ID: | Q16864 |
UCSC ID: | uc003voc.1 | OMIM ID: | 607160 |
Pubmed: | PMID8581736 PMID 8621738 | ||
CCDS IDs: | CCDSCCDS5807.1 |
V-type proton ATPase subunit F is an enzyme that in humans is encoded by the ATP6V1F gene.
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein. [provided by RefSeq, Jul 2008].
Function: Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Products for ATP6V1F gene
Catalog | Product Name | Application | Company |
GFS:E05919 | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F; ELISA kit | ELISA | n/a |
GFS:A05919 | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F; Anti | ANTIBODIES | n/a |
GFS:P05919 | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F; Protien | Protien | n/a |