Symbol: Name: ID: |
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 GFS:7136 |
Gene name: | ATP6V1G3 |
Chromosome: | 1q32.2 |
Previous Symbols: | |
Previous Names: | ATPase, H+ transporting, lysosomal 13kD, V1 subunit G isoform 3, "ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 3" |
Aliases: | ATP6G3, Vma10 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2450548 | Rat Genome Database ID: | RGD:1304635 |
HGNC ID: | HGNC:18265 | RefSeq IDs: | NM_133262 |
Entrez Gene ID: | 127124 | Ensembl Gene ID: | ENSG00000151418 |
VEGA IDs: | OTTHUMG00000035661 | UniProt ID: | Q96LB4 |
UCSC ID: | uc001gup.2 | OMIM ID: | |
Pubmed: | PMID9442887 | ||
CCDS IDs: | CCDSCCDS1395.1 CCDS CCDS1396.1 |
V-type proton ATPase subunit G 3 is an enzyme that in humans is encoded by the ATP6V1G3 gene.
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Products for ATP6V1G3 gene
Catalog | Product Name | Application | Company |
GFS:E07136 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3; ELISA kit | ELISA | n/a |
GFS:A07136 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3; Anti | ANTIBODIES | n/a |
GFS:P07136 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3; Protien | Protien | n/a |