Symbol: Name: ID: |
ALX1 ALX homeobox 1 GFS:4223 |
Gene name: | ALX1 |
Chromosome: | 12q21.31 |
Previous Symbols: | CART1 |
Previous Names: | cartilage paired-class homeoprotein 1 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:104621 | Rat Genome Database ID: | RGD:2273 |
HGNC ID: | HGNC:1494 | RefSeq IDs: | NM_006982 |
Entrez Gene ID: | 8092 | Ensembl Gene ID: | ENSG00000180318 |
VEGA IDs: | UniProt ID: | Q15699 | |
UCSC ID: | uc001tae.3 | OMIM ID: | 601527 |
Pubmed: | PMID8756334 PMID 7592751 | ||
CCDS IDs: | CCDSCCDS9028.1 |
ALX homeobox protein 1 is a protein that in humans is encoded by the ALX1 gene.
The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly. [provided by RefSeq, Jul 2008].
Function: Transcriptional activator that acts at a palindromic recognition sequence to enhance the activity of the SV40 and TK promoters. Functions as a repressor with the prolactin promoter in vivo. May play a role in chondrocyte differentiation and may also influence cervix development.
Products for ALX1 gene
Catalog | Product Name | Application | Company |
GFS:E04223 | ALX homeobox 1; ELISA kit | ELISA | n/a |
GFS:A04223 | ALX homeobox 1; Anti | ANTIBODIES | n/a |
GFS:P04223 | ALX homeobox 1; Protien | Protien | n/a |